Lisinopril is available in tablet form and is one of the best-known ACE inhibitors. Lisinopril is now one of the most common active ingredients in the treatment of high blood pressure.
However, taking the drug can lead to side effects and complaints, some of which are considerable, such as headaches, coughing, allergic reactions or even drowsiness in some cases. For this reason, Lisinopril is only available with a doctor’s prescription. Especially during or after pregnancy, it is essential to discuss the use of the drug with the doctor in charge.
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Where does the active ingredient come from?
However, the so-called ACE inhibitors have only been known since the 1980s and were originally found in the venom of some snake species. The venom that the snakes injected into their victims caused an abrupt drop in blood pressure and rendered the victims defenseless. Medical science wanted to take advantage of this effect and scientists began to change and improve the chemical structure of the substance contained in the snake venom and in this way developed all the ACE inhibitors known today, including Lisinopril.
The most common applications of Lisinopril
The well-known ACE inhibitor lisinopril is used for numerous complaints. Among the classic applications of the drug are typical complaints such as arterial hypertension, i.e. high blood pressure. However, the drug is also used for short-term treatment after a heart attack or for longer-term treatment of chronic heart failure.
More about the active ingredient and the effect of lisinopril
In principle, the human body has a very well-functioning system for regulating blood pressure. This system acts in a targeted manner, raising blood pressure when energy is needed and lowering it again during rest periods. However, if this system no longer functions properly, blood pressure disorders or elevated blood pressure can occur.
In most cases, the affected individuals only recognize the problem at a very late stage, when smaller vessels such as those in the eye or kidney have already suffered from the permanently elevated blood pressure. If the elevated blood pressure remains unnoticed or is not treated in time, it can also lead to serious complaints such as loss of eyesight or kidney dysfunction.
In order to be able to lower the blood pressure again durably and to be able to avoid serious consequential symptoms simple means like more sport, less fat nutrition or a clear weight reduction help mostly already. But since these remedies do not work fast enough, in many cases the doctor has to administer additional blood pressure-lowering drugs. One of these antihypertensive drugs is lisinopril.
How does Lisinopril work in the body?
Since Lisinopril belongs to the so-called group of ACE inhibitors (angiotensin-converting enzyme inhibitors), it promotes the formation of vasodilatory messengers (bradykinin) in the human body and at the same time reduces the formation of vasoconstrictor messengers (angiotensin-II). Due to this effect, the drug can effectively and permanently lower blood pressure while supporting the function of the heart.
The tablets are taken by mouth and the active ingredient is then absorbed directly from the intestine into the blood. Subsequently, it is distributed throughout the body and unfolds its effect. The active ingredient is finally excreted through the kidneys.
Lisinopril is usually taken in the form of tablets. However, there are major differences in dosage, depending on the patient’s symptoms and state of health. In most cases, however, a dosage of between 10 and 80 mg is prescribed. Depending on the type and severity of the disease, as already mentioned, there are serious differences in the dosage. Whereas adolescents and people with kidney problems should generally take only a low dosage.
The dosage is taken once a day. Ideally, after taking the tablet, a large glass of water is drunk, which promotes absorption in the body. If the tablets are always taken at the same time of day, the effect of the drug may also be favored.
Risks and side effects
Test trials have shown that the drug has caused side effects in up to 10 percent of the subjects treated with the active ingredient. These side effects include, in particular, severe headache, cough, gastrointestinal discomfort, hypotension and, in some cases, even brief drowsiness.
In rare cases, however, other side effects such as an allergic reaction to the active substance itself or significant circulatory disturbances in the fingers can be caused. Behavioral changes were also observed in a small percentage of subjects treated with the drug.
This page is designed to help people in the United States, Europe, Australia, New Zealand, Canada, and many other countries to find new information about Lisinopril, a popular high blood pressure medication. You can easily find out information on how to use this drug, its side effects, its chemical formula and how to purchase it.
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